Japan Bioinformatics

Simbiot provides a choice of two sophisticated time course analysis algorithms for Affymetrix and Illumina cDNA microarrays data.  Both functions are from Bioconductor (Gentleman, Carey et al. 2004): Timecourse (Tai and Speed 2009) and maSigPro (Conesa, Nueda et al. 2006).

 

References

Conesa, A., M. J. Nueda, et al. (2006). “maSigPro: a method to identify significantly differential expression profiles in time-course microarray experiments.” Bioinformatics 22(9): 1096-102.

Gentleman, R. C., V. J. Carey, et al. (2004). “Bioconductor: open software development for computational biology and bioinformatics.” Genome Biol 5(10): R80.

Tai, Y. C. and T. P. Speed (2009). “On gene ranking using replicated microarray time course data.” Biometrics 65(1): 40-51.

 

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